Biochemistry, Biophysics and Molecular Biology at California Polytechnic State University-San Luis Obispo
Bachelor's Degree
Analysis
Cal Poly San Luis Obispo's biochemistry program ranks among the state's strongest performers, outearning 80% of California schools offering this degree—including several UCs—though the small sample size (under 30 graduates) means individual outcomes vary more than these numbers suggest. At $57,538 in first-year earnings, graduates earn 36% more than the California median and a remarkable 51% above the national benchmark. The $17,500 typical debt load sits right at the state median, creating a debt-to-earnings ratio of just 0.30—meaning graduates owe roughly four months' salary.
The flat earnings trajectory between years one and four deserves attention, but context matters here: many biochemistry graduates pursue research positions, graduate school, or medical school applications during these early years, which can temporarily suppress earnings. Cal Poly's strong regional employer connections and hands-on "learn by doing" approach appear to give graduates immediate market value that compensates for this pattern. The program's selectivity (30% admission rate) and modest Pell grant enrollment (18%) suggest students arrive well-prepared academically.
For families weighing pre-med or research pathways, this program offers strong immediate job prospects with manageable debt. The caveat: with such a small cohort, your student's experience could differ significantly from these medians, so connecting with current students and recent alumni would be especially worthwhile here.
Where California Polytechnic State University-San Luis Obispo Stands
Earnings vs. debt across all biochemistry, biophysics and molecular biology bachelors's programs nationally
Programs in the upper-left quadrant (high earnings, low debt) offer the best value. Programs in the lower-right quadrant warrant careful consideration.
Earnings Distribution
How California Polytechnic State University-San Luis Obispo graduates compare to all programs nationally
California Polytechnic State University-San Luis Obispo graduates earn $58k, placing them in the 95th percentile of all biochemistry, biophysics and molecular biology bachelors programs nationally.
Earnings Over Time
How earnings evolve from 1 year to 4 years after graduation
Earnings trajectories vary significantly. Some programs show strong early returns that plateau; others start lower but accelerate. Consider where you want to be at year 4, not just year 1.
Compare to Similar Programs in California
Biochemistry, Biophysics and Molecular Biology bachelors's programs at peer institutions in California (49 total in state)
| School | Earnings (1yr) | Earnings (4yr) | Median Debt | Debt/Earnings |
|---|---|---|---|---|
| California Polytechnic State University-San Luis Obispo | $57,538 | $56,972 | $17,500 | 0.30 |
| California State University-San Marcos | $57,682 | — | $16,666 | 0.29 |
| California State University-Los Angeles | $50,428 | $41,157 | $16,730 | 0.33 |
| University of California-Santa Barbara | $49,100 | — | $9,500 | 0.19 |
| University of San Diego | $48,728 | $70,621 | $27,500 | 0.56 |
| California State University-Sacramento | $46,689 | — | $16,500 | 0.35 |
| National Median | $38,036 | — | $23,000 | 0.60 |
Other Biochemistry, Biophysics and Molecular Biology Programs in California
Compare tuition, earnings, and debt across California schools
| School | In-State Tuition | Earnings (1yr) | Debt |
|---|---|---|---|
| California State University-San Marcos San Marcos | $7,739 | $57,682 | $16,666 |
| California State University-Los Angeles Los Angeles | $6,813 | $50,428 | $16,730 |
| University of California-Santa Barbara Santa Barbara | $14,965 | $49,100 | $9,500 |
| University of San Diego San Diego | $56,444 | $48,728 | $27,500 |
| California State University-Sacramento Sacramento | $7,602 | $46,689 | $16,500 |
About This Data
Source: U.S. Department of Education College Scorecard (October 2025 release)
Population: Graduates who received federal financial aid (Title IV grants or loans). At California Polytechnic State University-San Luis Obispo, approximately 18% of students receive Pell grants. Students who did not receive federal aid are not included in these figures.
Earnings: Median earnings from IRS W-2 data for graduates who are employed and not enrolled in further education, measured 1 year after completion. Earnings are pre-tax and include wages, salaries, and self-employment income.
Debt: Median cumulative federal loan debt at graduation. Does not include private loans or Parent PLUS loans borrowed on behalf of students.
Sample Size: Based on 28 graduates with reported earnings and 29 graduates with debt data. Small samples may not be representative.