Median Earnings (1yr)
$57,538
95th percentile
80th percentile in California
Median Debt
$17,500
24% below national median

Analysis

Cal Poly San Luis Obispo's biochemistry program ranks among the state's strongest performers, outearning 80% of California schools offering this degree—including several UCs—though the small sample size (under 30 graduates) means individual outcomes vary more than these numbers suggest. At $57,538 in first-year earnings, graduates earn 36% more than the California median and a remarkable 51% above the national benchmark. The $17,500 typical debt load sits right at the state median, creating a debt-to-earnings ratio of just 0.30—meaning graduates owe roughly four months' salary.

The flat earnings trajectory between years one and four deserves attention, but context matters here: many biochemistry graduates pursue research positions, graduate school, or medical school applications during these early years, which can temporarily suppress earnings. Cal Poly's strong regional employer connections and hands-on "learn by doing" approach appear to give graduates immediate market value that compensates for this pattern. The program's selectivity (30% admission rate) and modest Pell grant enrollment (18%) suggest students arrive well-prepared academically.

For families weighing pre-med or research pathways, this program offers strong immediate job prospects with manageable debt. The caveat: with such a small cohort, your student's experience could differ significantly from these medians, so connecting with current students and recent alumni would be especially worthwhile here.

Where California Polytechnic State University-San Luis Obispo Stands

Earnings vs. debt across all biochemistry, biophysics and molecular biology bachelors's programs nationally

Earnings Distribution

How California Polytechnic State University-San Luis Obispo graduates compare to all programs nationally

Earnings Over Time

How earnings evolve from 1 year to 4 years after graduation

School1 Year4 YearsGrowth
California Polytechnic State University-San Luis Obispo$57,538$56,972-1%
University of Southern California$34,468$72,935+112%
University of San Diego$48,728$70,621+45%
University of California-Davis$42,266$65,761+56%
California State University-Fullerton$38,869$65,436+68%

Compare to Similar Programs in California

Biochemistry, Biophysics and Molecular Biology bachelors's programs at peer institutions in California (49 total in state)

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SchoolIn-State TuitionEarnings (1yr)Earnings (4yr)Median DebtDebt/Earnings
California Polytechnic State University-San Luis ObispoSan Luis Obispo$11,075$57,538$56,972$17,5000.30
California State University-San MarcosSan Marcos$7,739$57,682$16,6660.29
California State University-Los AngelesLos Angeles$6,813$50,428$41,157$16,7300.33
University of California-Santa BarbaraSanta Barbara$14,965$49,100$9,5000.19
University of San DiegoSan Diego$56,444$48,728$70,621$27,5000.56
California State University-SacramentoSacramento$7,602$46,689$16,5000.35
National Median$38,036$23,0000.60

Career Paths

Occupations commonly associated with biochemistry, biophysics and molecular biology graduates

Natural Sciences Managers

Plan, direct, or coordinate activities in such fields as life sciences, physical sciences, mathematics, statistics, and research and development in these fields.

$161,180/yrJobs growth:Bachelor's degree

Clinical Research Coordinators

Plan, direct, or coordinate clinical research projects. Direct the activities of workers engaged in clinical research projects to ensure compliance with protocols and overall clinical objectives. May evaluate and analyze clinical data.

$161,180/yrJobs growth:Bachelor's degree

Water Resource Specialists

Design or implement programs and strategies related to water resource issues such as supply, quality, and regulatory compliance issues.

$161,180/yrJobs growth:Bachelor's degree

Biochemists and Biophysicists

Study the chemical composition or physical principles of living cells and organisms, their electrical and mechanical energy, and related phenomena. May conduct research to further understanding of the complex chemical combinations and reactions involved in metabolism, reproduction, growth, and heredity. May determine the effects of foods, drugs, serums, hormones, and other substances on tissues and vital processes of living organisms.

$103,650/yrJobs growth:Doctoral or professional degree

Medical Scientists, Except Epidemiologists

Conduct research dealing with the understanding of human diseases and the improvement of human health. Engage in clinical investigation, research and development, or other related activities.

$100,590/yrJobs growth:Doctoral or professional degree

Microbiologists

Investigate the growth, structure, development, and other characteristics of microscopic organisms, such as bacteria, algae, or fungi. Includes medical microbiologists who study the relationship between organisms and disease or the effects of antibiotics on microorganisms.

$87,330/yrJobs growth:Bachelor's degree

Biological Science Teachers, Postsecondary

Teach courses in biological sciences. Includes both teachers primarily engaged in teaching and those who do a combination of teaching and research.

$83,980/yrJobs growth:

Biological Technicians

Assist biological and medical scientists. Set up, operate, and maintain laboratory instruments and equipment, monitor experiments, collect data and samples, make observations, and calculate and record results. May analyze organic substances, such as blood, food, and drugs.

$52,000/yrJobs growth:Bachelor's degree

Food Science Technicians

Work with food scientists or technologists to perform standardized qualitative and quantitative tests to determine physical or chemical properties of food or beverage products. Includes technicians who assist in research and development of production technology, quality control, packaging, processing, and use of foods.

$48,480/yrJobs growth:Associate's degree

Biological Scientists, All Other

All biological scientists not listed separately.

Bioinformatics Scientists

Conduct research using bioinformatics theory and methods in areas such as pharmaceuticals, medical technology, biotechnology, computational biology, proteomics, computer information science, biology and medical informatics. May design databases and develop algorithms for processing and analyzing genomic information, or other biological information.

Molecular and Cellular Biologists

Research and study cellular molecules and organelles to understand cell function and organization.

About This Data

Source: U.S. Department of Education College Scorecard (October 2025 release)

Population: Graduates who received federal financial aid (Title IV grants or loans). At California Polytechnic State University-San Luis Obispo, approximately 18% of students receive Pell grants. Students who did not receive federal aid are not included in these figures.

Earnings: Median earnings from IRS W-2 data for graduates who are employed and not enrolled in further education, measured 1 year after completion. Earnings are pre-tax and include wages, salaries, and self-employment income.

Debt: Median cumulative federal loan debt at graduation. Does not include private loans or Parent PLUS loans borrowed on behalf of students.

Sample Size: Based on 28 graduates with reported earnings and 29 graduates with debt data. Small samples may not be representative.